Predictive Monitor CEO Laurie Masiello Named One of New Hampshire's 2026 Outstanding Women in Business

NASHUA, N.H. — September 9, 2026 — Laurie Masiello, Co-Founder and Chief Executive Officer of Nashua-based Predictive Monitor, has been named a 2026 Outstanding Woman in Business by New Hampshire Business Review, recognizing a career that has spanned more than four decades of entrepreneurship, life sciences innovation, community leadership and advocacy for the next generation of women in business.

“I’m incredibly honored by this recognition, and what makes it especially meaningful to me is how much has changed for women since I first started in business,” said Masiello. “I want young women coming into business and STEM today to know that they can lead, they can build companies, they can change industries, and they can elevate the women around them.”

Laurie and her husband, John, began their first company Masy BioServices from their home in 1984. They grew to more than 200 employees with a worldwide customer base serving the pharmaceutical, biotechnology and medical device industries.

When the couple sold Masy BioServices in 2021, retirement would have been an understandable next chapter.

Instead, they started another company, Predictive Monitor.

“I’ve had a front-row seat to Laurie’s determination, courage, and incredible heart for more than 55 years, as her husband, her business partner, and, without question, her biggest supporter,” said John Masiello, Co-Founder and Chief Innovation Officer of Predictive Monitor. “I’ve watched Laurie build businesses from the ground up, overcome challenges, break barriers, and earn the respect of an entire industry.”

Today, Laurie leads the New Hampshire-based technology company focused on pharmaceutical and life sciences organizations identifying developing refrigeration problems before equipment failure puts valuable and potentially life-saving products at risk.

“Most people would have taken the money and run, but not John and Laurie,” said Walter J. Dwyer IV, Chief Executive Officer of Main Street Bank, in supporting Masiello’s nomination. “She is the Chief Executive Officer for a reason: she knows how to get things done.”

That ability to execute has become a theme among the people who have worked with Laurie over the years.

One of the attorneys who represented the Masiellos during the sale of Masy BioServices recalled the extraordinary pace of the transaction, which was completed in roughly four months without an investment banker.

“I say ‘somehow,’ but in truth, Laurie was the ‘somehow,’” the attorney wrote. “She was not merely a contributor to that accomplishment; she was a driving force behind it.”

Masiello’s leadership has also been defined by what happened after the deal closed.

Following the sale, Laurie and John chose to distribute bonuses to more than 200 employees, including two people who had started working for the company only that week.

That people-first philosophy has followed Masiello throughout her career.

“No, we work together,” Masiello would routinely emphasize to employees who said they worked for her, according to longtime colleague Mark Gindi.

Gindi also recalled asking Masiello why she didn’t simply retire after selling the business. Her response was immediate:

“Mark, our industry needs OverShield. How can I relax after being a critical part of the supply chain for years?”

OverShield^®, Predictive Monitor’s predictive analytics solution, uses sensor data and baseline performance to provide life sciences organizations earlier visibility into developing refrigeration-system problems, allowing them to intervene before a potentially catastrophic failure.

For Masiello, protecting those systems ultimately means protecting what is inside them: research, biologics, pharmaceuticals and other products that can represent years of work and, ultimately, affect patients.

Her influence, however, extends well beyond the companies she has built.

Masiello became the first woman President of the New England Chapter of the Parenteral Drug Association and has held leadership roles with organizations including the International Society for Pharmaceutical Engineering and the Nashoba Valley Chamber of Commerce. She has supported scholarship programs, mentored students and early-career professionals, and helped open doors for women entering the life sciences industry.

One of those professionals is Lindsay McGrail, Ph.D., who first met Masiello as an undergraduate biotechnology student.

“Laurie personally introduced me to everyone in the room at my first PDA meeting outside of the student chapter,” McGrail recalled. “That speaks volumes to the mentor, but more importantly the sponsor that Laurie is for the next generation of talent.”

McGrail would eventually become a leader within the organization herself while earning her doctorate and credits Masiello with helping shape the trajectory of her career.

“As proud as I am of everything she has accomplished professionally, what makes me most proud is the difference Laurie has made in the lives of the people around her,” John Masiello shared. “She has always believed that true success isn’t measured simply by what you accomplish yourself, but by the opportunities you create for others and the people you help succeed along the way.”

Masiello’s experience breaking barriers began long before she became a CEO.

She has often shared a story from grade school, when she entered an essay contest her brother had previously won. A nun told the young Masiello that her essay was one of the best she had read, but that Masiello’s excellent writing skills didn’t matter because “girls can’t win.”

Masiello never accepted that premise.

Decades later, while attending an industry event at Gillette Stadium, her mother remarked on the number of men in attendance and how remarkable it was that so many seemed to know her daughter.

Masiello clarified, “Mom, they don’t just know me. They respect me.”

That respect is reflected throughout the testimonials submitted on her behalf, from bankers and attorneys to employees, customers, industry colleagues and professionals she mentored.

“Laurie has earned tremendous respect throughout the biotechnology and pharmaceutical industries because people know she is genuine,” Gindi wrote. “They know she tells the truth. They know she operates with integrity. And they know that when Laurie commits to solving a problem, she will do everything in her power to find a solution.”

For Masiello, being named one of New Hampshire’s Outstanding Women in Business is recognition not simply of what she has built, but of a career spent proving what women can build when they are free to grow and thrive.

“Success has never just been about building a company for me,” Masiello said. “It’s about the people you bring with you, the opportunities you create and whether you leave something better than you found it. I’ve had people open doors for me during my career, and I’ve always believed it’s my responsibility to hold those doors open for the people coming behind me.”

Today, Masiello continues to lead Predictive Monitor from New Hampshire, developing technology designed to move life sciences organizations from reacting to equipment failures to predicting and preventing them.

And more than 50 years after a young girl was told that girls couldn’t win, Masiello is still proving otherwise.

“I know how hard Laurie has worked, the sacrifices she has made, and how much of herself she has given to her family, her employees, her customers, and her community,” John Masiello continued. “After more than five decades beside her, I am still amazed by her strength, her compassion, and her determination to make a difference. To see Laurie recognized as one of New Hampshire’s 2026 Outstanding Women in Business is incredibly special to me. I could not be prouder of the woman she is, the life we have built together, and the legacy she continues to create. I truly cannot think of anyone more deserving of this recognition.”

About Predictive Monitor

Predictive Monitor is a Nashua, New Hampshire-based technology company serving the life sciences industry. Its OverShield^® predictive analytics solution is designed to identify developing refrigeration-system issues before they become costly failures, enabling pharmaceutical, biotechnology and other life sciences organizations to protect critical operations and the valuable products entrusted to their care.

Photo by John Hession, courtesy New Hampshire Business Review.